| Item type |
共通(1) |
| 公開日 |
2017-07-26 |
| タイトル |
|
|
タイトル |
Decreased levels of irisin, a skeletal muscle cell-derived myokine, are related to emphysema associated with chronic obstructive pulmonary disease |
|
言語 |
en |
| 作成者 |
杉山, 由香里
| en |
Sugiyama, Yukari
Osaka City University
|
| ja-Kana |
スギヤマ, ユカリ
|
| ja |
杉山, 由香里
|
Search repository
浅井, 一久
山田, 一宏
| en |
Yamada, Kazuhiro
Osaka City University
|
| ja-Kana |
ヤマダ, カズヒロ
|
| ja |
山田, 一宏
|
Search repository
呉家, 由子
井尻, 尚樹
渡辺, 徹也
| en |
Watanabe, Tetsuya
Osaka City University
|
| ja-Kana |
ワタナベ, テツヤ
|
| ja |
渡辺, 徹也
|
Search repository
金澤, 博
平田, 一人
|
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2017 Sugiyama et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
| 主題 |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
慢性閉塞性肺疾患 |
| 主題 |
|
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
chronic obstructive pulmonary disease |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
COPD |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
emphysema |
| 主題 |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
irisin |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Nrf2 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cigarette-smoke extract |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
CSE |
| 主題 |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
apoptosis |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: Cigarette smoking-induced oxidant–antioxidant imbalance is a factor that contributes to the pathogenesis of COPD through epithelial cell apoptosis. Irisin is a skeletal muscle cell-derived myokine associated with physical activity. Irisin is also known to decrease oxidant-induced apoptosis in patients with diabetes mellitus. However, the correlation between irisin and emphysema in COPD and its role in epithelial cell apoptosis remains unknown. / Subjects and methods: Forty patients with COPD were enrolled in this study. Pulmonary function tests and measurements of the percentage of low-attenuation area on high-resolution computed tomography images were performed, and the results were evaluated for correlation with serum irisin levels.... |
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言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This work was supported in part by research grants from the Japan Society for the Promotion of Science (JSPS) Kakenhi grant 15K09185 to KA. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Dove Medical Press |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 識別子 |
|
|
識別子 |
https://doi.org/10.2147/COPD.S126233 |
|
識別子タイプ |
DOI |
| 関連情報 |
|
|
|
識別子タイプ |
NCID |
|
|
関連識別子 |
AA12158595 |
| 書誌情報 |
en : International Journal of Chronic Obstructive Pulmonary Disease
巻 2017,
号 12,
p. 765-772,
発行日 2017-03-02
|
| 収録物識別子 |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1176-9106 |
本文 (1.7 MB)
