{"created":"2024-10-31T02:13:46.662135+00:00","id":2020355,"links":{},"metadata":{"_buckets":{"deposit":"e8cd245f-bb17-4bd2-8852-95ca0a8e36f0"},"_deposit":{"created_by":7,"id":"2020355","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2020355"},"status":"published"},"_oai":{"id":"oai:ocu-omu.repo.nii.ac.jp:02020355","sets":["1623632832836:1721355153493"]},"author_link":[],"item_1617186331708":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Challenges in developing mucosal vaccines and antibodies against infectious diarrhea in children","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Tokuhara, Daisuke","creatorNameLang":"en"},{"creatorName":"トクハラ, ダイスケ","creatorNameLang":"ja-Kana"},{"creatorName":"徳原, 大介","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000060448751","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060448751"},{"nameIdentifier":"0000-0002-2441-5062","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-2441-5062"}]}]},"item_1617186499011":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is the peer reviewed version of the following article: Pediatrics International, Vol.60, Issu.3, p.214-223., which has been published in final form athttps://doi.org/10.1111/ped.13497 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"主題","attribute_value_mlt":[{"subitem_subject":"ロタウイルス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"コレラ菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"antibody fragment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mucosal immunity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rice-based vaccine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rotavirus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Vibrio cholerae","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Infectious diarrhea in children can be life-threatening and imposes a large economic burden on healthcare systems, therefore more effective prophylactic and therapeutic drugs are needed urgently. Because most of the pathogens responsible for childhood diarrhea infect the gastrointestinal mucosa, providing protective immunity at the mucosal surface is an ideal way to control pathogen invasion and toxic activity. Mucosal (e.g., oral, nasal) vaccines are superior to systemic (subcutaneous or intramuscular) vaccination for conferring both mucosal and systemic pathogen-specific immune responses, and for the past 50 years, great efforts has been focused on the development of cost-effective mucosal vaccines....","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"This work was supported by grants from the Japan Society for the Promotion of Science (Grants-in-Aid for Research Activity Start-up 24890202 to D.T., Scientific Research 16K10039 and 25461558 to D.T., and Challenging Exploratory Research 40419700 to D.T.), the Danone Institute of Japan Foundation (D.T.), the Japan Foundation for Pediatric Research (D.T.), the SENSHIN Medical Research Foundation (D.T.), and the Ohyama Health Foundation (D.T.).","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_1617186783814":{"attribute_name":"識別子","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"https://doi.org/10.1111/ped.13497"}]},"item_1617186920753":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"1442-200X","subitem_source_identifier_type":"ISSN"}]},"item_1617187056579":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"223","bibliographicPageStart":"214","bibliographicVolumeNumber":"60","bibliographic_titles":[{"bibliographic_title":"Pediatrics International","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_b1a7d7d4d402bcce","subitem_version_type":"AO"}]},"item_1617353299429":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/ped.13497","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"AA11631585","subitem_relation_type_select":"NCID"}}]},"item_1722232185104":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-05"}],"displaytype":"detail","filename":"1442200X-60-3-214.pdf","filesize":[{"value":"858.7 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://ocu-omu.repo.nii.ac.jp/record/2020355/files/1442200X-60-3-214.pdf"},"version_id":"15edec6d-97bf-4cbb-b77c-c9354c4d46fd"}]},"item_1722577087681":{"attribute_name":"記事種別等","attribute_value_mlt":[{"subitem_description":"Review Article","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1725590125188":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_title":"Challenges in developing mucosal vaccines and antibodies against infectious diarrhea in children","item_type_id":"40002","owner":"7","path":["1721355153493"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-07-05"},"publish_date":"2019-07-05","publish_status":"0","recid":"2020355","relation_version_is_last":true,"title":["Challenges in developing mucosal vaccines and antibodies against infectious diarrhea in children"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-31T02:13:57.541114+00:00"}