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The final authenticated version is available online at: https://doi.org/10.1007/s11010-018-3466-x . See Springer Nature terms of use.　https://www.springer.com/gp/open-access/publication-policies/aam-terms-of-use .","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"主題","attribute_value_mlt":[{"subitem_subject":"星細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Hepatic stellate cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Senescence","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Secretory factor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ERK1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"2","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Fibroblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Senescent hepatic stellate cells (senescent HSCs) are found in patients with liver cirrhosis and have been thought to be involved in the development of hepatocellular carcinoma (HCC) in mice via the senescence-associated secretory proteins. However, in humans, which secretory proteins are involved and what regulate their expression remain unclear. In the current study, we characterized senescence-associated β-galactosidase-positive senescent human HSCs (hHSCs) induced by repetitive passaging....","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"This work was supported by The Uehara Memorial Foundation, The Osaka Medical Research Foundation for Intractable Diseases, The Tokyo Biochemical Research Foundation, The Osaka City University Strategic Research Grant 2016 for young researchers, JSPS KAKENHI Grant Number JP26870501 and JP17K18012, and a Grant for Research Program on Hepatitis from the Japan Agency for Medical Research and Development (AMED) Grant Number 16fk0210104h0001.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_1617186783814":{"attribute_name":"識別子","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"https://doi.org/10.1007/s11010-018-3466-x"}]},"item_1617186920753":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"1573-4919","subitem_source_identifier_type":"ISSN"}]},"item_1617187056579":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-05-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"19","bibliographicPageStart":"7","bibliographicVolumeNumber":"455","bibliographic_titles":[{"bibliographic_title":"Molecular and Cellular Biochemistry","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_b1a7d7d4d402bcce","subitem_version_type":"AO"}]},"item_1617353299429":{"attribute_name":"関連情報","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s11010-018-3466-x","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"AA12103298","subitem_relation_type_select":"NCID"}}]},"item_1722232185104":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-26"}],"displaytype":"detail","filename":"15734919-455-1_2-7.pdf","filesize":[{"value":"663.5 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://ocu-omu.repo.nii.ac.jp/record/2020102/files/15734919-455-1_2-7.pdf"},"version_id":"4114fbc6-1cba-465a-a36d-11e3db070bf3"}]},"item_1722577087681":{"attribute_name":"記事種別等","attribute_value_mlt":[{"subitem_description":"Original Paper","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1725590125188":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_title":"Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells","item_type_id":"40002","owner":"7","path":["1721355153493"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-05-26"},"publish_date":"2020-05-26","publish_status":"0","recid":"2020102","relation_version_is_last":true,"title":["Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-31T01:47:13.023340+00:00"}