{"created":"2024-10-31T01:21:02.637914+00:00","id":2019877,"links":{},"metadata":{"_buckets":{"deposit":"fe24c13a-6cbe-410c-8f83-2e8bebb656f3"},"_deposit":{"created_by":7,"id":"2019877","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"2019877"},"status":"published"},"_oai":{"id":"oai:ocu-omu.repo.nii.ac.jp:02019877","sets":["1623632832836:1721355153493"]},"author_link":[],"item_1617186331708":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Assessing liver stiffness with conventional cut‐off values overestimates liver fibrosis staging in patients who received the Fontan procedure","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Cho, Yuki","creatorNameLang":"en"},{"creatorName":"チョウ, ユキ","creatorNameLang":"ja-Kana"},{"creatorName":"趙, 有季","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000080779398","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000080779398/"},{"nameIdentifier":"20182526","nameIdentifierScheme":"RESEARCHMAP","nameIdentifierURI":"https://researchmap.jp/20182526"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Kabata, Daijiro","creatorNameLang":"en"},{"creatorName":"カバタ, ダイジロウ","creatorNameLang":"ja-Kana"},{"creatorName":"加葉田, 大志朗","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000040793435","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000040793435"},{"nameIdentifier":"0000-0002-1243-4928","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-1243-4928"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City General Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Ehara, Eiji","creatorNameLang":"en"},{"creatorName":"エバラ, エイジ","creatorNameLang":"ja-Kana"},{"creatorName":"江原, 英治","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Yamamoto, Akira","creatorNameLang":"en"},{"creatorName":"ヤマモト, アキラ","creatorNameLang":"ja-Kana"},{"creatorName":"山本, 晃","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000060419695","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060419695"},{"nameIdentifier":"0000-0002-4567-9745","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-4567-9745"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Kurume University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Mizuochi, Tatsuki","creatorNameLang":"en"},{"creatorName":"ミズオチ, タツキ","creatorNameLang":"ja-Kana"},{"creatorName":"水落, 建輝","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000020368921","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000020368921"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Kinki University Nara Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Mushiake, Sotaro","creatorNameLang":"en"},{"creatorName":"ムシアケ, ソウタロウ","creatorNameLang":"ja-Kana"},{"creatorName":"虫明, 聡太郎","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000090291947","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000090291947"},{"nameIdentifier":"strmushiake","nameIdentifierScheme":"RESEARCHMAP","nameIdentifierURI":"https://researchmap.jp/strmushiake"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Kurume University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Kusano, Hironori","creatorNameLang":"en"},{"creatorName":"クサノ, ヒロノリ","creatorNameLang":"ja-Kana"},{"creatorName":"草野, 弘宣","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000030569380","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000030569380"},{"nameIdentifier":"0000-0002-9911-2007","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-9911-2007"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Kuwae, Yuko","creatorNameLang":"en"},{"creatorName":"クワエ, ユウコ","creatorNameLang":"ja-Kana"},{"creatorName":"桑江, 優子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000050597557","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000050597557/"},{"nameIdentifier":"kuwaeyu","nameIdentifierScheme":"RESEARCHMAP","nameIdentifierURI":"https://researchmap.jp/kuwaeyu"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City General Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Suzuki, Tsugutoshi","creatorNameLang":"en"},{"creatorName":"スズキ, ツグトシ","creatorNameLang":"ja-Kana"},{"creatorName":"鈴木, 嗣敏","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"0000-0002-1549-0212","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-1549-0212"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Uchida-Kobayashi, Sawako","creatorNameLang":"en"},{"creatorName":"ウチダ(コバヤシ), サワコ","creatorNameLang":"ja-Kana"},{"creatorName":"打田, 佐和子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000060382074","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060382074"},{"nameIdentifier":"0000-0002-5198-3102","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-5198-3102"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Morikawa Internal Medicine Clinic","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Morikawa, Hiroyasu","creatorNameLang":"en"},{"creatorName":"モリカワ, ヒロヤス","creatorNameLang":"ja-Kana"},{"creatorName":"森川, 浩安","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000060457992","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060457992"},{"nameIdentifier":"read0138980","nameIdentifierScheme":"RESEARCHMAP","nameIdentifierURI":"https://researchmap.jp/read0138980"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City General Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Amano-Teranishi, Yuga","creatorNameLang":"en"},{"creatorName":"アマノ(テラニシ), ユウガ","creatorNameLang":"ja-Kana"},{"creatorName":"天野, 優雅","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000070733947","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000070733947"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City General Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Kioka, Kiyohide","creatorNameLang":"en"},{"creatorName":"キオカ, キヨヒデ","creatorNameLang":"ja-Kana"},{"creatorName":"木岡, 清英","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Jogo, Atsushi","creatorNameLang":"en"},{"creatorName":"ジョウゴ, アツシ","creatorNameLang":"ja-Kana"},{"creatorName":"城後, 篤志","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"0000-0003-1974-4790","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0003-1974-4790"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Isoura, Yoshiharu","creatorNameLang":"en"},{"creatorName":"イソウラ, ヨシハル","creatorNameLang":"ja-Kana"},{"creatorName":"磯浦, 喜晴","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"0000-0003-3885-432X","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0003-3885-432X"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hamazaki, Takashi","creatorNameLang":"en"},{"creatorName":"ハマザキ, タカシ","creatorNameLang":"ja-Kana"},{"creatorName":"濱崎, 考史","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000040619798","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000040619798"},{"nameIdentifier":"m9124565","nameIdentifierScheme":"RESEARCHMAP","nameIdentifierURI":"https://researchmap.jp/m9124565"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University, Osaka City General Hospita","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Murakami, Yosuke","creatorNameLang":"en"},{"creatorName":"ムラカミ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"村上, 洋介","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Osaka City University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Tokuhara, Daisuke","creatorNameLang":"en"},{"creatorName":"トクハラ, ダイスケ","creatorNameLang":"ja-Kana"},{"creatorName":"徳原, 大介","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"1000060448751","nameIdentifierScheme":"KAKEN2","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060448751"},{"nameIdentifier":"0000-0002-2441-5062","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-2441-5062"}]}]},"item_1617186499011":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"クリエイティブ・コモンズ　表示 - 非営利 - 改変禁止 4.0 国際 ","subitem_rights_language":"ja","subitem_rights_resource":"https://creativecommons.org/licenses/by-nc-nd/4.0/ "},{"subitem_rights":"Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International ","subitem_rights_language":"en","subitem_rights_resource":"https://creativecommons.org/licenses/by-nc-nd/4.0/ "},{"subitem_rights":"© 2021 The Authors.","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"主題","attribute_value_mlt":[{"subitem_subject":"肝線維化","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"肝硬度","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"超音波エラストグラフィ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Fontan procedure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hepatic venous pressure gradient","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"liver fibrosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"liver stiffness","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transient elastography","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究グループは、Fontan術後の長期経過における合併症として、従来の検査手法(超音波エラストグラフィや血液検査)では的確な評価が難しい特異な肝線維化の進展が認められることを明らかにしました。先天性の複雑心疾患に対するFontan手術は、国内で年間400件近く行われる頻度の高い手術です。22名の術後患者(術後中央値14.7年)の方々から肝組織を採取し、従来の検査手法(超音波エラストグラフィや血液検査)が組織学的な線維化の程度を反映するのか検討しました。その結果、中程度の線維化が半数以上に、高度な線維化が約3割の方々に認められ、それらの線維化は一般的な肝硬変とは異なり類洞域を中心とした特異なパターンを示すことがわかりました。さらに、肝硬度は術後経時的に上昇するにもかかわらず、門脈圧の影響を受け組織学的な線維化を的確に反映せず、また、線維化マーカーとして用いられる4型コラーゲンやFIB-4 indexなどの血液マーカーも組織学的線維化を反映しないことがわかりました。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Aim: Patients who undergo the Fontan procedure for complex congenital heart disease are prone to liver cirrhosis. Liver stiffness (LS) reflects liver fibrosis stage in patients with chronic viral hepatitis; however, its accuracy in predicting liver fibrosis stage in Fontan patients is controversial. We aimed to clarify the correlation between LS and liver fibrosis stage in Fontan patients....","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"This work was supported by a grant from the Japan Society for the Promotion of Science (Grant-in-Aid for Young Scientists 18K15725 to Y.C.) and the National Center for Global Health and Medicine (Intramural Research Fund 30A2001 [to D.T.]).","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_1617186783814":{"attribute_name":"識別子","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"https://doi.org/10.1111/hepr.13627"}]},"item_1617186920753":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"1872-034X","subitem_source_identifier_type":"ISSN"}]},"item_1617187056579":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"602","bibliographicPageStart":"593","bibliographicVolumeNumber":"51","bibliographic_titles":[{"bibliographic_title":"Hepatology Research","bibliographic_titleLang":"en"}]}]},"item_1617258105262":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1722232185104":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-19"}],"displaytype":"detail","filename":"1872034x-51-5-593.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://ocu-omu.repo.nii.ac.jp/record/2019877/files/1872034x-51-5-593.pdf"},"version_id":"48a4426f-c3f6-4ee2-81a3-6cbefb8891bb"}]},"item_1722577087681":{"attribute_name":"記事種別等","attribute_value_mlt":[{"subitem_description":"ORIGINAL ARTICLE","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_1725590125188":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_title":"Assessing liver stiffness with conventional cut‐off values overestimates liver fibrosis staging in patients who received the Fontan procedure","item_type_id":"40002","owner":"7","path":["1721355153493"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-05-19"},"publish_date":"2021-05-19","publish_status":"0","recid":"2019877","relation_version_is_last":true,"title":["Assessing liver stiffness with conventional cut‐off values overestimates liver fibrosis staging in patients who received the Fontan procedure"],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2024-10-31T01:21:12.695487+00:00"}